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Risk Factors for Cognitive Impairment in Intensive Care Unit Survivors

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KMID : 1221920200130030075
°­Áö¿¬ ( Kang Ji-Yeon ) - Dong-A University Department of Nursing

À̺¸°æ ( Yi Bo-Kyung ) - Dong-A University Hospital Cardiovascular Intensive Care Unit

Abstract

Purpose : This study aimed to identify the prevalence and risk factors of cognitive impairment in survivors discharged from the intensive care unit (ICU).

Methods : This secondary analysis study utilized data from a multicenter prospective cohort of post-ICU patients. We analyzed the data of 175 patients enrolled in the primary cohort who completed the cognitive function evaluation three months after ICU discharge. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) scale. The cut-off points for cognitive impairment were < 23 for face-to-face evaluation and < 18 for telephone evaluation.

Results : The prevalence of cognitive impairment three months after ICU discharge was 32.6%. Significant risk factors for cognitive impairment were age ¡Ã 60 years (OR=10.52, 95% CI=3.65¡­30.33, p <.001), education < high school graduation (OR=2.53, 95% CI=1.07¡­6.01, p =.035), unplanned ICU admission (OR=4.01, 95% CI=1.45-11.14, p =.008), and delirium in the ICU (OR=4.33, 95% CI=1.08-17.23, p =.038).

Conclusion : ICU nurses should use preemptive strategies to reduce post-ICU cognitive impairment of patients with risk factors. It is necessary to frequently assess and detect early delirium in critically ill patients, while attempting various non-pharmacological interventions.
KeyWords
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Intensive care unit, Cognitive dysfunction, Delirium, Patients, Risk factors
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